ABSTRACT
The objective of this study was to evaluate the efficacy of intermittent oral diazepam for reducing the recurrence of febrile seizures.Prince Rushed military hospital north of Jordan. Prospective controlled study of 280 patients, who were admitted to pediatric ward with first febrile seizures and were r and omized into two groups, one group received short-term prophylaxis for 12 months with oral diazepam 2.5Mg for children less than 7Kg, 5Mg for children weighing 7-15Kg and 10mg diazepam for children weighing more than 15kg and then continued after the temperature >38.5c, the control group received no prophylaxis Short-term diazepam prophylaxis reduces the recurrence rate of febrile seizures to one fifth that is from 43% to 8.2 [p<0.003] when the first febrile seizures are simple and to one-fourth that from 62% to 16% when the first febrile seizures are complex, with mild side effects of diazepam. Short-term prophylaxis with oral diazepam is effective in prevention of recurrence of febrile seizures, with mild side effects